An overview of pancreatic beta-cell defects in human type 2 diabetes: implications for treatment.

@article{Marchetti2008AnOO,
  title={An overview of pancreatic beta-cell defects in human type 2 diabetes: implications for treatment.},
  author={Piero Marchetti and Francesco Dotta and Davide Lauro and Francesco Purrello},
  journal={Regulatory peptides},
  year={2008},
  volume={146 1-3},
  pages={4-11}
}
Type 2 diabetes is the most common form of diabetes in humans. It results from a combination of factors that impair beta-cell function and tissue insulin sensitivity. However, growing evidence is showing that the beta-cell is central to the development and progression of this form of diabetes. Reduced islet and/or insulin-containing cell mass or volume in Type 2 diabetes has been reported by several authors. Furthermore, studies with isolated Type 2 diabetic islets have consistently shown both… CONTINUE READING
44 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 44 extracted citations

Similar Papers

Loading similar papers…