An overview of natural polymers for oral insulin delivery.

  title={An overview of natural polymers for oral insulin delivery.},
  author={Touri{\~n}o Sonia and Chandra Prakash Sharma},
  journal={Drug discovery today},
  volume={17 13-14},
Current therapy for diabetes mellitus through oral anti-diabetic drugs and subcutaneous administration of insulin suffers from serious disadvantages, such as patient noncompliance and occasional hypoglycemia. Moreover, these approaches doesn't mimic the normal physiological pattern of insulin release. Oral route would be the most convenient and preferred route if it is available. Polymeric nano and/or microparticles, either natural or synthetic have been used as matrices for oral insulin… CONTINUE READING