An overview of isolated and syndromic oesophageal atresia

@article{Genevive2007AnOO,
  title={An overview of isolated and syndromic oesophageal atresia},
  author={David Genevi{\`e}ve and Loïc De Pontual and Jeanne Amiel and Sabine Sarnacki and Stanislas Lyonnet},
  journal={Clinical Genetics},
  year={2007},
  volume={71}
}
Oesophageal atresia (OA) and/or tracheo‐oesophageal fistula (TOF) are frequent malformations observed in approximately one in 3500 births. OA/TOF can be divided clinically into isolated OA (IOA) and syndromic OA (SOA) when associated with other features, the most frequent being cardiac, limb and vertebral malformations or anal atresia. SOA is observed in 50% of patients and can be subdivided into several causative groups comprising environmental agents, chromosomal disorders, malformative… 
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