An overview of clinical trials involving inhibitors of angiogenesis and their mechanism of action

Abstract

Angiogenesis is a biologic process whereby endothelial cells divide and migrate to form new blood vessels. This process is required in physiological conditions, but is also a necessary requirement for solid tumors to grow and metastasize. Over the last several years, the growth factors that have both a positive and negative influence on tumor angiogenesis… (More)
DOI: 10.1023/A:1005770612294

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