An overview of a Sertoli cell transplantation model to study testis morphogenesis and the role of the Sertoli cells in immune privilege

@inproceedings{Kaur2017AnOO,
  title={An overview of a Sertoli cell transplantation model to study testis morphogenesis and the role of the Sertoli cells in immune privilege},
  author={Gurvinder Kaur and Scott Vadala and Jannette M. Dufour},
  booktitle={Environmental epigenetics},
  year={2017}
}
Advanced testicular germ cells, expressing novel cell surface and intracellular proteins, appear after the establishment of central tolerance and thus are auto-immunogenic. However, due to testis immune privilege these germ cells normally do not evoke a detrimental immune response. The Sertoli cell (SC) barrier (also known as the blood-testis barrier… CONTINUE READING