An overview: antitumor immunity in breast cancer assayed by tube leukocyte adherence inhibition.

@article{Flores1977AnOA,
  title={An overview: antitumor immunity in breast cancer assayed by tube leukocyte adherence inhibition.},
  author={Margarita Flores and Jacques Marti and N. Grosser and John K Macfarlane and David M. P. Thomson},
  journal={Cancer},
  year={1977},
  volume={39 2},
  pages={494-505}
}
The adherence to glass of human peripheral blood leukocytes (PBL) incubated with tumor antigen in vitro, is specifically inhibited if the PBL are sensitized to the antigen. The presence of leukocyte adherence inhibition (LAI) to tumor extracts indicates the presence of systemic antitumor immunity. By the tube leukocyte adherence inhibition assay (tube LAI), it was shown that 85% (191 of 223) Stage I and II, 45% (15 of 34) Stage III and 29% (30 of 103) Stage IV breast cancer patients had LAI… CONTINUE READING
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