An outer membrane protein, OmpK, is an effective vaccine candidate for Vibrio harveyi in Orange-spotted grouper (Epinephelus coioides).

@article{Ningqiu2008AnOM,
  title={An outer membrane protein, OmpK, is an effective vaccine candidate for Vibrio harveyi in Orange-spotted grouper (Epinephelus coioides).},
  author={Li Ningqiu and Bai Junjie and Wu Shuqin and Fu Xiaozhe and Lao Haihua and Ye Xing and Shi Cunbin},
  journal={Fish & shellfish immunology},
  year={2008},
  volume={25 6},
  pages={829-33}
}
The outer membrane proteins of the fish pathogen, Vibrio harveyi, have a role in interaction between bacterium and host and are potential candidates for vaccine development. In this study, the gene encoding an outer membrane protein, OmpK, which serves as the receptor for broad-host-range vibriophage KVP40 in V. harveyi, was isolated and characterized. Then the OmpK gene coding for mature peptide was subcloned into prokaryotic expression vector pBV220 and transformed into Escherichia coli DH5… CONTINUE READING
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