An outbreak of a nosocomial NDM-1-producing Klebsiella pneumoniae ST147 at a teaching hospital in mainland China.

  title={An outbreak of a nosocomial NDM-1-producing Klebsiella pneumoniae ST147 at a teaching hospital in mainland China.},
  author={Xiaojuan Wang and Xiu-li Xu and Zongwei Li and Hongbin Chen and Qi Wang and Peihong Yang and Chun-jiang Zhao and Ming-Mei Ni and Hui Wang},
  journal={Microbial drug resistance},
  volume={20 2},
A total of 1,870 nonduplicate clinical Enterobacteriaceae from 13 teaching hospitals located in 11 provinces of mainland China from 2011 to 2012 were screened for the presence of the blaNDM gene. The high-throughput MiSeq sequencing method and comparative genomics were used to analyze the genetic environment of blaNDM among these isolates. Three blaNDM-1-carrying Klebsiella pneumoniae (0.16%, 3/1,870), isolated from a teaching hospital in Xi'an, exhibited high levels of resistance to all… 

NDM-1-producing Enterobacteriaceae in a teaching hospital in Shanghai, China: IncX3-type plasmids may contribute to the dissemination of blaNDM-1.

  • Hongping QuXiaoli Wang Jingyong Sun
  • Biology, Medicine
    International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases
  • 2015

Outbreak of nosocomial NDM-1-producing Klebsiella pneumoniae ST1419 in a neonatal unit.

Emergence of ST147 Klebsiella pneumoniae Producing OXA-204 Carbapenemase in a University Hospital, Tunisia.

This study reports the second case worldwide of an OXA-204-producing K. pneumoniae isolate from the same country, however, in a different genetic background, as well as investigating the first carbapenem-resistant Klebsiella pneumoniae isolates investigated.

NDM-producing Enterobacteriaceae in a Chinese hospital, 2014-2015: identification of NDM-producing Citrobacterwerkmanii and acquisition of blaNDM-1-carrying plasmid in vivo in a clinical Escherichia coli isolate.

In conclusion, an NDM-1-producing isolate of C. werkmanii was identified, which had not been reported previously, and might have emerged as the main platforms mediating the spread of the blaNDM genes in China.

First report in China of Enterobacteriaceae clinical isolates coharboring blaNDM-1 and blaIMP-4 drug resistance genes.

Coexistence of blaNDM-1 and blaIMP-4 in these clinical isolates may herald the emergence of a new pattern of drug resistance.

New Delhi Metallo-β-Lactamase 1-Producing Klebsiella pneumoniae ST719 Isolated from a Neonate in China.

A New Delhi metallo-β-lactamase 1 (NDM-1)-producing K. pneumoniae strain KP14003 from a neonate in Beijing, China is reported, which causes great challenges to the treatment of clinical infections.

First Case of NDM-1-Producing Klebsiella pneumoniae in Annaba University Hospital, Algeria.

This study comprises the first identification of NDM-1-producing K. pneumoniae in Algeria and confirms the concerning worldwide dissemination of this carbapenemase that involves the emergence of the IncR plasmid and the success of the ST147 clonal complex harboring it.

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The possibility of human-to- food animal transfer of blaNDM-1-producing E. coli from diseased pigs in China is suggested, highlighting the need for surveillance of carbapenemase producers among bacteria from food animals.



Emergence of blaNDM-1 among Klebsiella pneumoniae ST15 and novel ST1031 clinical isolates in China.

Outbreak of carbapenem-resistant enterobacteriaceae containing blaNDM-1, Ontario, Canada.

  • S. BorgiaO. Lastovetska R. Melano
  • Medicine, Biology
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
  • 2012
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Identification and characterization of a novel incompatibility group X3 plasmid carrying blaNDM-1 in Enterobacteriaceae isolates with epidemiological links to multiple geographical areas in China

The findings indicate the worrisome involvement of an epidemic plasmid in the dissemination of NDM-1 in China and the first description of IncX3 plasmids carrying blaNDM-1.

Nosocomial Clustering of NDM-1-Producing Klebsiella pneumoniae Sequence Type 340 Strains in Four Patients at a South Korean Tertiary Care Hospital

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Identification of New Delhi Metallo-β-lactamase 1 in Acinetobacter lwoffii of Food Animal Origin

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