An orally active angiotensin-(1-7) inclusion compound and exercise training produce similar cardiovascular effects in spontaneously hypertensive rats.

@article{Bertagnolli2014AnOA,
  title={An orally active angiotensin-(1-7) inclusion compound and exercise training produce similar cardiovascular effects in spontaneously hypertensive rats.},
  author={Mariane Bertagnolli and Karina Rabello Casali and Frederico Barbosa de Sousa and Katya Rigatto and Lenice Kappes Becker and S{\'e}rgio Henrique Souza Santos and Lucinara Dadda Dias and Graziela H{\"u}nning Pinto and Daniela Ravizzoni Dartora and Beatriz D Schaan and Ruben Dario Sinisterra Milan and Maria Cl{\'a}udia Costa Irigoyen and Robson Augusto Souza Santos},
  journal={Peptides},
  year={2014},
  volume={51},
  pages={65-73}
}
Low angiotensin-(1-7) (Ang-(1-7)) concentration is observed in some cardiovascular diseases and exercise training seems to restore its concentration in the heart. Recently, a novel formulation of an orally active Ang-(1-7) included in hydroxy-propyl-beta-cyclodextrin (HPB-CD) was developed and chronically administered in experimental models of cardiovascular diseases. The present study examined whether chronic administration of HPB-CD/Ang-(1-7) produces beneficial cardiovascular effects in… CONTINUE READING
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