An oral poliovirus vaccine trial in Costa Rica.

@article{Paul1962AnOP,
  title={An oral poliovirus vaccine trial in Costa Rica.},
  author={John R. Paul and Dorothy M. Horstmann and John T. Riordan and Jr. Edward M. Opton and James C. Niederman and E. Peter Isacson and Robert H. Green},
  journal={Bulletin of the World Health Organization},
  year={1962},
  volume={26 3},
  pages={
          311-29
        }
}
Early in the course of the 1959 nationwide oral poliovirus vaccination campaign in Costa Rica, a small, special and intensive study of oral vaccination was initiated there by the Yale Poliomyelitis Study Unit. The aims were to determine the effectiveness of vaccination, as measured by the rate of antibody conversions and antibody rises induced by the trivalent Lederle oral vaccine when given in two doses to a population of young children living in a tropical environment; to determine the… CONTINUE READING

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