An optimized synthesis of manganese meso-tetra(4-sulfonatophenyl)porphine: A tumor-selective MRI contrast agent

@inproceedings{Bockhorst1994AnOS,
  title={An optimized synthesis of manganese meso-tetra(4-sulfonatophenyl)porphine: A tumor-selective MRI contrast agent},
  author={Kurt Bockhorst and Mathias Hoehn-Berlage},
  year={1994}
}
Abstract The preparation of the potential magnetic resonance imaging (MRI) tumor-selective contrast agent manganese meso-tetra(4-sulfonatophenyl)porphine (MnTPPS4) was optimized to yield a product with high purity (⩾-98%) in large amounts (> 1 g). The presented simplified purification method may contribute to the application of MnTPPS4 in clinical trials. 

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Labelling of manganese-based magnetic resonance imaging (MRI) contrast agents with the positron emitter 51Mn, as exemplified by manganese-tetraphenyl-porphin-sulfonate (MnTPPS4).

  • Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine
  • 2005
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