An optimized murine model of ferric chloride-induced arterial thrombosis for thrombosis research.

@article{Wang2005AnOM,
  title={An optimized murine model of ferric chloride-induced arterial thrombosis for thrombosis research.},
  author={Xinkang Wang and Lin Xu},
  journal={Thrombosis research},
  year={2005},
  volume={115 1-2},
  pages={95-100}
}
INTRODUCTION/OBJECTIVES Animal models are important tools in thrombosis research and preclinical drug development. Ferric chloride has been widely used to induce arterial thrombosis in a variety of species. However, almost all previous reports applied a very high concentration of ferric chloride (10-60%) to induce thrombus formation leading to difficulties in evaluating the efficacy of antithrombotic agents. Thus, the purpose of this study was to refine the ferric-chloride-induced thrombosis… CONTINUE READING

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