An optimal experimental design for the development of preservative heart solutions.

@article{Ferrera2002AnOE,
  title={An optimal experimental design for the development of preservative heart solutions.},
  author={R David Ferrera and Pierre Michel and Guylaine Hadour and Claire Rodriguez and Michel Ovize and Roger Phan Tan Luu},
  journal={The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation},
  year={2002},
  volume={21 2},
  pages={260-70}
}
BACKGROUND The aim of this study was to determine the optimal composition of a new medium for long-term hypothermic heart preservation. METHODS The independent effects of 19 compounds were evaluated using an in vitro porcine model. Tissue viability was assessed by measuring the reduction of methyltetrazolium salt, oxygen consumption and energetic compound… CONTINUE READING