An operator-induced conformational change in the C-terminal domain of the lambda repressor.

Abstract

4,4'-bis(1-anilino-8-naphthalenesulfonic acid (Bis-ANS), an environment-sensitive fluorescent probe for hydrophobic region of proteins, binds specifically to the C-terminal domain of lambda repressor. The binding is characterized by positive cooperativity, the magnitude of which is dependent on protein concentration in the concentration range where dimeric… (More)

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Cite this paper

@article{Saha1992AnOC, title={An operator-induced conformational change in the C-terminal domain of the lambda repressor.}, author={Ranendra Narayan Saha and U K Banik and Sreejani Bandopadhyay and Nitai Chandra Mandal and Bhabatarak Bhattacharyya and S Roy}, journal={The Journal of biological chemistry}, year={1992}, volume={267 9}, pages={5862-7} }