An open trial of plasma exchange in childhood-onset obsessive-compulsive disorder without poststreptococcal exacerbations.

@article{Nicolson2000AnOT,
  title={An open trial of plasma exchange in childhood-onset obsessive-compulsive disorder without poststreptococcal exacerbations.},
  author={Rob Nicolson and Susan E. Swedo and Marge C Lenane and Joshua Bedwell and Marianne Wudarsky and Peter A. Gochman and Susan D Hamburger and Judith L. Rapoport},
  journal={Journal of the American Academy of Child and Adolescent Psychiatry},
  year={2000},
  volume={39 10},
  pages={1313-5}
}
Patients with childhood-onset obsessive-compulsive disorder (OCD) with symptom exacerbations following streptococcal infections benefit from treatment with plasma exchange. In this study, 5 patients with treatment-refractory OCD without a history of streptococcus-related exacerbations underwent an open 2-week course of therapeutic plasma exchange. Behavioral ratings, completed at baseline and 4 weeks after the initial treatment, included the Clinical Global Impressions Scale and the Yale-Brown… CONTINUE READING

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