An open trial of oral sildenafilin antidepressant-induced sexual dysfunction.

@article{Fava1998AnOT,
  title={An open trial of oral sildenafilin antidepressant-induced sexual dysfunction.},
  author={Maurizio Fava and Meridith A. Rankin and Jonathan E. Alpert and Andrew Nierenberg and John J. Worthington},
  journal={Psychotherapy and psychosomatics},
  year={1998},
  volume={67 6},
  pages={
          328-31
        }
}
BACKGROUND Sildenafil is a selective inhibitor of cyclic GMP-specific phosphodiesterase type 5 that has been associated with greater improvement of erectile function compared to placebo among men with erectile dysfunction. The goal of our study was to evaluate its efficacy in a small sample of outpatients with antidepressant-induced sexual dysfunction. METHODS We studied the first 14 depressed outpatients (9 men and 5 women; mean age: 46.4 +/- 8.4) who were consecutively treated with oral… CONTINUE READING

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