An open-source analytical platform for analysis of <ce:italic>C. elegans</ce:italic> swimming-induced paralysis

@article{Hardaway2014AnOA,
  title={An open-source analytical platform for analysis of <ce:italic>C. elegans</ce:italic> swimming-induced paralysis},
  author={J Andrew Hardaway and Jing Wang and Paul A. Fleming and Katherine A. Fleming and Randy D. Blakely},
  journal={Journal of Neuroscience Methods},
  year={2014},
  volume={232},
  pages={58-62}
}
BACKGROUND The nematode Caenhorhabditis elegans offers great power for the identification and characterization of genes that regulate behavior. In support of this effort, analytical methods are required that provide dimensional analyses of subcomponents of behavior. Previously, we demonstrated that loss of the presynaptic dopamine (DA) transporter, dat-1, evokes DA-dependent Swimming-Induced Paralysis (Swip) (Mcdonald et al., 2007), a behavior compatible with forward genetic screens (Hardaway… CONTINUE READING
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