An open pilot study of nefazodone in depression with anger attacks: relationship between clinical response and receptor binding.

@article{Mischoulon2002AnOP,
  title={An open pilot study of nefazodone in depression with anger attacks: relationship between clinical response and receptor binding.},
  author={David Mischoulon and Darin D. Dougherty and Kathryn A. Bottonari and Robert L Gresham and Shamsah B. Sonawalla and Alan J. Fischman and Maurizio Fava},
  journal={Psychiatry research},
  year={2002},
  volume={116 3},
  pages={151-61}
}
Nefazodone has been widely used as an antidepressant, but it has not been tested for depression with anger attacks. In an open study, we administered nefazodone (maximum 600 mg/day) for 12 weeks to 16 outpatients who had major depression with anger attacks. Assessment instruments comprised the Structured Clinical Interview for DSM-IV (SCID), Anger Attacks Questionnaire (AAQ), 17-item Hamilton Rating Scale for Depression (HAM-D-17), Clinician Global Impression Scale (CGI), Symptom Questionnaire… CONTINUE READING
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