An open letter to our readers on the use of antibodies

@article{Saper2005AnOL,
  title={An open letter to our readers on the use of antibodies},
  author={Clifford B. Saper},
  journal={Journal of Comparative Neurology},
  year={2005},
  volume={493}
}
  • C. Saper
  • Published 26 December 2005
  • Biology
  • Journal of Comparative Neurology
The use of immunohistochemistry has become ubiquitous in neuroscience. A large majority of papers now published in The Journal of Comparative Neurology use immunohistochemistry, and some papers may employ a battery of ten or more antibodies to examine issues of colocalization or cell typing. This pattern has resulted in a flood of new information. . . .but also a flood of misinformation. The Journal has repeatedly, over the last few years, received distressed communications from authors, who… 

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