An open-label trial of St. John's Wort (Hypericum perforatum) in obsessive-compulsive disorder.


BACKGROUND Recent interest in and evidence for the efficacy of St. John's wort (Hypericum perforatum) for the treatment of mild-to-moderate depression has led to speculation about its efficacy in other disorders. Hypericum's mechanism of action is postulated to be via inhibition of the synaptosomal uptake of serotonin. As such, there is a suggestion that… (More)


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