An open-label, crossover study of a new phosphate-binding agent in haemodialysis patients: ferric citrate.

@article{Yang2002AnOC,
  title={An open-label, crossover study of a new phosphate-binding agent in haemodialysis patients: ferric citrate.},
  author={Wu-chang Yang and Chwei-shiun Yang and Chun-Chen Hou and Tsai-Hung Wu and Eric W. Young and Chen H Hsu},
  journal={Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association},
  year={2002},
  volume={17 2},
  pages={265-70}
}
BACKGROUND Hyperphosphataemia contributes to secondary hyperparathyroidism and renal osteodystrophy in patients with end-stage renal disease (ESRD). Calcium salts are widely employed to bind dietary phosphate (P) but they may promote positive net calcium balance and metastatic calcification. We recently reported that ferric compounds bind intestinal phosphate in studies of normal and azotemic rats. METHODS To extend this observation, we performed an open-label, random order, crossover… CONTINUE READING
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