An on-chip pollutant toxicity determination based on marine microalgal swimming inhibition.

@article{Feng2016AnOP,
  title={An on-chip pollutant toxicity determination based on marine microalgal swimming inhibition.},
  author={Cheng-Yu Feng and Jun-Feng Wei and Ya-jie Li and Yu-Suo Yang and Yun-hua Wang and Ling Lu and Guo-xia Zheng},
  journal={The Analyst},
  year={2016},
  volume={141 5},
  pages={
          1761-71
        }
}
We report the use of microalgal swimming behavior as a sensor signal integrated into microfluidics for a rapid and high-throughput determination of pollutant toxicity. There are two types of chip. A poly(dimethylsiloxane) (PDMS) 12-well chip, used for optimization of experimental conditions (i.e. light level, temperature, initial cellular density and exposure time), can perform twelve parallel tests simultaneously. In a concentration gradient generator (CGG) chip, a CGG connected with… CONTINUE READING
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