An octamer of core histones in solution: central role of the H3-H4 tetramer in the self-assembly.

@article{RuizCarrillo1979AnOO,
  title={An octamer of core histones in solution: central role of the H3-H4 tetramer in the self-assembly.},
  author={Adolf Ruiz-Carrillo and Jos{\'e} Luis Jorcano},
  journal={Biochemistry},
  year={1979},
  volume={18 5},
  pages={760-8}
}
The association of histones H2A, H2B, H3, and H4 in solution has been studied. In 2 M NaCl and at neutral pH they can assemble in a complex in which each histone is present in equimolar amounts. The complex has a weight average molecular weight of 98,000 (+/- 3700) and a sedimentation coefficient (so20,w) of 4.8. The value of the weight average molecular… CONTINUE READING