An objective case definition of lipodystrophy in HIV-infected adults: a case-control study.

@article{Carr2003AnOC,
  title={An objective case definition of lipodystrophy in HIV-infected adults: a case-control study.},
  author={Andrew Carr and Sean Emery and Matthew V. Law and Rebekah Puls and Jens D. Lundgren and William G. Powderly},
  journal={Lancet},
  year={2003},
  volume={361 9359},
  pages={726-35}
}
BACKGROUND Lipodystrophy (peripheral lipoatrophy, central fat accumulation, and lipomatosis) is a common and disfiguring problem in adult patients with HIV-1 infection on antiretrovirals. However, an objective, validated definition of the disorder does not exist. We aimed to develop an objective, sensitive, specific, and broadly applicable case definition of HIV lipodystrophy. METHODS In a case-control study, 1081 consecutive, HIV-infected, adult outpatients (261 [15%] women) without active… CONTINUE READING

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