Corpus ID: 205018121

An lmmunoglobulin Heavy Chain Variable Region Gene Is Generated from Three Segments of DNA : VH

@inproceedings{Huang2004AnLH,
  title={An lmmunoglobulin Heavy Chain Variable Region Gene Is Generated from Three Segments of DNA : VH},
  author={H. Huang and M. Davis and K. Calame and L. Hood},
  year={2004}
}
We have determined the sequences of separate germline genetic elements which encode two parts of a mouse immunoglobulin heavy chain variable region. These elements, termed gene segments, are heavy chain counterparts of the variable (V) and joining (J) gene segments of immunoglobulin light chains. The VH gene segment encodes amino acids l-101 and the JH gene segment encodes amino acids 107-l 23 of the S107 phosphorylcholine-binding V,, region. This J,, gene segment and two other J,, gene… Expand
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