An isolated perfused dog lung preparation for the study of cyclic GMP metabolism: effects of sodium nitroprusside and oxygen.

Abstract

The intact, isolated perfused dog lung was evaluated as a model for studies directed at defining the role of oxidative modulation of lung cyclic GMP metabolism in pulmonary function. Sodium nitroprusside added to the perfusion blood increased the cyclic GMP content of lung over 4-fold in a dose-dependent manner. Although sodium nitroprusside administration… (More)

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Cite this paper

@article{Braughler1982AnIP, title={An isolated perfused dog lung preparation for the study of cyclic GMP metabolism: effects of sodium nitroprusside and oxygen.}, author={J Mark Braughler and Mikel Maron}, journal={European journal of pharmacology}, year={1982}, volume={78 2}, pages={187-93} }