An investigational tetravalent meningococcal serogroups A, C, W-135 and Y-tetanus toxoid conjugate vaccine co-administered with Infanrix™ hexa is immunogenic, with an acceptable safety profile in 12-23-month-old children.

@article{Knuf2011AnIT,
  title={An investigational tetravalent meningococcal serogroups A, C, W-135 and Y-tetanus toxoid conjugate vaccine co-administered with Infanrix™ hexa is immunogenic, with an acceptable safety profile in 12-23-month-old children.},
  author={Markus Knuf and Anna Pantazi-Chatzikonstantinou and Ulrich Pfletschinger and Irmingard Tichmann-Schumann and Hartwig Maurer and Lothar Maurer and Thomas Fischbach and Henrike Zinke and Heidemarie Pankow-Culot and Vassiliki Papaevangelou and V{\'e}ronique Bianco and Marie van der Wielen and Jacqueline Miller},
  journal={Vaccine},
  year={2011},
  volume={29 25},
  pages={4264-73}
}
Tetravalent meningococcal serogroups ACWY conjugate vaccines will provide an advantage to those at most risk of invasive meningococcal disease; namely young children. Co-administration of ACWY-TT with DTaP-HBV-IPV/Hib was assessed in a randomized trial in 793 children aged 12-23 months. Pre-specified criteria for non-inferiority of immunogenicity following co-administration versus separate ACWY-TT and DTaP-HBV-IPV/Hib administration were reached. One month post-vaccination, ≥ 97.3% of ACWY-TT… CONTINUE READING
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