An investigation of the neurotrophic factor genes GDNF, NGF, and NT3 in susceptibility to ADHD.

@article{Syed2007AnIO,
  title={An investigation of the neurotrophic factor genes GDNF, NGF, and NT3 in susceptibility to ADHD.},
  author={Zahoor Syed and Frank Dudbridge and Lindsey Kent},
  journal={American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics},
  year={2007},
  volume={144B 3},
  pages={375-8}
}
Attention deficit hyperactivity disorder (ADHD) is a common, highly heritable, neurodevelopmental disorder with onset in early childhood. Genes involved in neuronal development and growth are, thus, important etiological candidates and neurotrophic factors have been hypothesized to play a role in the pathogenesis of ADHD. Glial derived neurotrophic factor (GDNF), nerve growth factor (NGF (beta subunit)), and neurotrophic factor 3 (NT3) are members of the neurotrophin family and are involved in… CONTINUE READING

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