An investigation of the neuroprotective effects of Curcumin in a model of Homocysteine - induced oxidative stress in the rat's brain

@inproceedings{Ataie2010AnIO,
  title={An investigation of the neuroprotective effects of Curcumin in a model of Homocysteine - induced oxidative stress in the rat's brain},
  author={Amin Ataie and Masoumeh Sabetkasaei and Abbas Haghparast and Akbar Hajizadeh moghaddam and Ramin Ataie and Sh. Nasiraei Moghaddam},
  booktitle={Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences},
  year={2010}
}
BACKGROUND AND THE PURPOSE OF THE STUDY Aging is the major risk factor for neurodegenerative diseases and oxidative stress is involved in the pathophysiology of them. Oxidative stress can induce neuronal damages and modulate intracellular signaling, ultimately leading to neuronal death by apoptosis or necrosis. In this study, the possible antioxidant and neuroprotective properties of the natural polyphenolic antioxidant compound, curcumin against homocysteine (Hcy) neurotoxicity was… CONTINUE READING
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