An investigation of the effects of hippocampal lesions in rats on pre- and postoperatively acquired spatial memory in a complex environment.

@article{Winocur2010AnIO,
  title={An investigation of the effects of hippocampal lesions in rats on pre- and postoperatively acquired spatial memory in a complex environment.},
  author={Gordon Winocur and Morris Moscovitch and R. Shayna Rosenbaum and Melanie J Sekeres},
  journal={Hippocampus},
  year={2010},
  volume={20 12},
  pages={1350-65}
}
In previous work, we showed that adult rats that were reared socially for 3 months in a complex (village) environment retained allocentric spatial memory for that environment following hippocampal lesions (Winocur et al., (2005) Nat Neurosci 8:273–275). In the present series of experiments, we showed that 3 months of postoperative rearing did not confer the same benefits (Experiment 1), although hippocampal groups, with or without rearing experience, exhibited spatial learning after extensive… CONTINUE READING

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