An investigation of sterile immunity against toxoplasmosis in rats.

@article{Freyre2004AnIO,
  title={An investigation of sterile immunity against toxoplasmosis in rats.},
  author={Alvaro Freyre and Jes{\'u}s Falc{\'o}n and Josefina M{\'e}ndez and Oscar Correa and Diana Morgades and Ana Rodr{\'i}guez},
  journal={Experimental parasitology},
  year={2004},
  volume={107 1-2},
  pages={14-9}
}
The non-persistent BK strain was examined for its ability to induce sterile immunity in Wistar rats. Groups of 2-9 Wistar rats were inoculated subcutaneously with 5 x 10(4) BK strain tachyzoites per rat. Two months later, 46 rats were dosed by gavage with 2 x 10(1) cysts of the C, ME-49, Prugniaud, C-56, Elg, M-7741 or M3 strains. Another 26 rats were inoculated with 10(3) oocysts of the ME49, M7741, Bear or Hopa-Hopa strains of Toxoplasma gondii. After 2 months, the rats were euthanized and… CONTINUE READING