An investigation into variability in the therapeutic response to deferiprone in patients with thalassemia major.

Abstract

Data suggest a large variability in the effectiveness of the orally active iron chelator, deferiprone, in inducing a sustained decrease in body iron to concentrations compatible with the avoidance of complications from iron overload. We analyzed 19 patients with thalassemia major who were undergoing long-term therapy with deferiprone (75 mg/kg/day every 8… (More)

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@article{DiavCitrin1999AnII, title={An investigation into variability in the therapeutic response to deferiprone in patients with thalassemia major.}, author={Orna Diav-Citrin and Gordana Atanackovic and G. Koren}, journal={Therapeutic drug monitoring}, year={1999}, volume={21 1}, pages={74-81} }