An investigation into the role of chemokines in haemopoietic stem cell quiescence

@inproceedings{Sinclair2015AnII,
  title={An investigation into the role of chemokines in haemopoietic stem cell quiescence},
  author={Amy Kiernan Sinclair},
  year={2015}
}
Haemopoietic stem cells (HSC) maintain lifelong haemopoiesis through the monitoring and production of cells from multiple haemopoietic cell lineages. A key property of HSC is their ability to maintain quiescence. Quiescence refers to a state of inactivity in which the cell is not dividing and remains dormant. It is this property of the HSC that is thought to maintain genomic integrity and to allow the HSC to sustain haemopoiesis over the period of a lifetime. However, the regulation of… CONTINUE READING

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