An investigation into the effects of the hierarchical structure of tendon fascicles on micromechanical properties

@article{Screen2004AnII,
  title={An investigation into the effects of the hierarchical structure of tendon fascicles on micromechanical properties},
  author={Hazel R. C. Screen and D. A. Lee and Dan L. Bader and Julia C Shelton},
  journal={Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine},
  year={2004},
  volume={218},
  pages={109 - 119}
}
  • H. Screen, D. Lee, +1 author J. Shelton
  • Published 1 February 2004
  • Materials Science, Medicine
  • Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine
Abstract During physiological loading, a tendon is subjected to tensile strains in the region of up to 6 per cent. These strains are reportedly transmitted to cells, potentially initiating specific mechano-transduction pathways. The present study examines the local strain fields within tendon fascicles subjected to tensile strain in order to determine the mechanisms responsible for fascicle extension. A hierarchical approach to the analysis was adopted, involving micro and macro examination… 
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TLDR
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TLDR
It is concluded that stromal tenocytes likely do not play a major role in anabolic repair of tendon matrix microdamage, but rather mediate catabolic matrix breakdown and communication with extrinsic cells that are able to effect tissue repair.
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It is concluded that the collagen fibrils underwent significantly greater recruitment (fibril strain relative to global tissue strain) at higher strain rates.
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