An investigation into the association among preterm birth, cytokine gene polymorphisms and periodontal disease.

@article{Moore2004AnII,
  title={An investigation into the association among preterm birth, cytokine gene polymorphisms and periodontal disease.},
  author={Suzanne Moore and Maximilian Ide and Manjit Randhawa and James J. Walker and Janet G Reid and Nigel A. B. Simpson},
  journal={BJOG : an international journal of obstetrics and gynaecology},
  year={2004},
  volume={111 2},
  pages={125-32}
}
OBJECTIVE To investigate a putative relationship between preterm delivery and the carriage of polymorphic genes that code for the cytokines interleukin-1beta (IL-1beta) at codon +3953 and tumour necrosis factor-alpha (TNF-alpha) at codon -308 in a group of postpartum women and to elucidate if the concurrent presence of periodontal disease increased the risk of preterm delivery in this group. DESIGN Case-control study SETTING Postnatal wards at Guy's and St Thomas' Hospital Trust… CONTINUE READING