An investigation into the alpha-adrenoceptor mediating renal nerve-induced calcium reabsorption by the rat kidney.

@article{Johns1986AnII,
  title={An investigation into the alpha-adrenoceptor mediating renal nerve-induced calcium reabsorption by the rat kidney.},
  author={Edward James Johns and Joachim von Manitius},
  journal={British journal of pharmacology},
  year={1986},
  volume={89 1},
  pages={91-7}
}
An investigation was undertaken in pentobarbitone-anaesthetized rats to determine the sub-type of alpha-adrenoceptor responsible for the renal nerve-induced increases in the reabsorption of calcium and sodium by the tubules of the kidney. Stimulation of the renal nerves at low frequencies (0.8-1.5 Hz) did not change either renal blood flow or glomerular filtration rate but significantly reduced urine flow by 32%, calcium excretion by 36% and absolute and fractional sodium excretions by 36% and… CONTINUE READING
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