An inversion truncating the creA gene of Aspergillus nidulans results in carbon catabolite derepression.

@article{Arst1990AnIT,
  title={An inversion truncating the creA gene of Aspergillus nidulans results in carbon catabolite derepression.},
  author={Herbert N. Arst and David Tollervey and Celia E. A. Dowzer and Joan M. Kelly},
  journal={Molecular microbiology},
  year={1990},
  volume={4 5},
  pages={851-4}
}
The creAd-30 mutation leading to carbon catabolite derepression in Aspergillus nidulans is a pericentric inversion, having one breakpoint within the creA gene on the left arm of chromosome I and the other breakpoint between binG and yA on the right arm. The left-arm breakpoint alters the creA transcript. The likelihood that the inversion truncates creA centrally strengthens a previous proposal that derepression is the phenotype of loss-of-function mutations in creA. 

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