An introduction to mixed models and joint modeling: analysis of valve function over time.

Abstract

An important target of many clinical studies is to identify biomarkers, including risk scores, with strong prognostic capabilities. While biomarker evaluations are commonly utilized to predict the progress of the disease at single time points, appropriate statistical tools to assess the prognostic value of serial biomarker evaluation are rarely used. The… (More)
DOI: 10.1016/j.athoracsur.2012.02.049

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@article{Andrinopoulou2012AnIT, title={An introduction to mixed models and joint modeling: analysis of valve function over time.}, author={Eleni-Rosalina Andrinopoulou and Dimitris Rizopoulos and Ruyun Jin and Ad J. J. C. Bogers and Emmanuel Lesaffre and Johanna J M Takkenberg}, journal={The Annals of thoracic surgery}, year={2012}, volume={93 6}, pages={1765-72} }