An introduction to TRP channels.

  title={An introduction to TRP channels.},
  author={Ian Scott Ramsey and Markus Delling and David E. Clapham},
  journal={Annual review of physiology},
The aim of this review is to provide a basic framework for understanding the function of mammalian transient receptor potential (TRP) channels, particularly as they have been elucidated in heterologous expression systems. Mammalian TRP channel proteins form six-transmembrane (6-TM) cation-permeable channels that may be grouped into six subfamilies on the basis of amino acid sequence homology (TRPC, TRPV, TRPM, TRPA, TRPP, and TRPML). Selected functional properties of TRP channels from each… 

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