An intimate liaison: spatial organization of the endoplasmic reticulum-mitochondria relationship.

@article{Brito2010AnIL,
  title={An intimate liaison: spatial organization of the endoplasmic reticulum-mitochondria relationship.},
  author={Olga Martins de Brito and Luca Scorrano},
  journal={The EMBO journal},
  year={2010},
  volume={29 16},
  pages={2715-23}
}
Organelle localization is often crucial to properly modulate cellular functions and signalling cascades. For example, the distribution of organelles in axons is crucial for their function and is dysregulated in several diseases. Similarly, relative positioning of two or more organelles is also important to perform certain specialized processes. Perhaps, the best-known form of interorganellar organization is that between endoplasmic reticulum (ER) and mitochondria. Close communication between… CONTINUE READING

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