An intersubunit contact stimulating transcription initiation by E coli RNA polymerase: interaction of the alpha C-terminal domain and sigma region 4.

Abstract

The C-terminal domain of the Escherichia coli RNA polymerase (RNAP) alpha subunit (alphaCTD) stimulates transcription initiation by interacting with upstream (UP) element DNA and a variety of transcription activators. Here we identify specific substitutions in region 4.2 of sigma 70 (sigma(70)) and in alphaCTD that decrease transcription initiation from… (More)

Topics

Cite this paper

@article{Ross2003AnIC, title={An intersubunit contact stimulating transcription initiation by E coli RNA polymerase: interaction of the alpha C-terminal domain and sigma region 4.}, author={Wilma Ross and David Schneider and Brian J. Paul and Aaron Mertens and Richard L Gourse}, journal={Genes & development}, year={2003}, volume={17 10}, pages={1293-307} }