An international collaborative family-based whole-genome linkage scan for high-grade myopia.

@article{Li2009AnIC,
  title={An international collaborative family-based whole-genome linkage scan for high-grade myopia.},
  author={Yi-Ju Li and Jeremy A. Guggenheim and Anuradha Bulusu and Ravikanth Metlapally and Diana Abbott and François J Malecaze and Patrick Calvas and Thomas Rosenberg and Sandrine Paget and Rosalind C Creer and George Kirov and Michael J. Owen and Bei Zhao and Tristan White and David A. Mackey and Terri L. Young},
  journal={Investigative ophthalmology \& visual science},
  year={2009},
  volume={50 7},
  pages={
          3116-27
        }
}
PURPOSE Several nonsyndromic high-grade myopia loci have been mapped primarily by microsatellite markers and a limited number of pedigrees. In this study, whole-genome linkage scans were performed for high-grade myopia, using single nucleotide polymorphisms (SNPs) in 254 families from five independent sites. METHODS Genomic DNA samples from 1411 subjects were genotyped (Linkage Panel IVb; Illumina, San Diego, CA). Linkage analyses were performed on 1201 samples from 10 Asian, 12 African… 

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