An international case-control study of glutathione transferase and functionally related polymorphisms and risk of primary adult brain tumors.

Abstract

BACKGROUND Glutathione transferases (GST) detoxify environmental and endogenous compounds and levels of two polymorphic GST proteins, GSTM3 and GSTP1, are high in the brain. Previous studies of GSTM3 and GSTP1 polymorphisms and adult brain tumor risk have produced inconsistent results, whereas the GSTM3 -63 variant is newly identified and, therefore, has… (More)

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@article{Schwartzbaum2007AnIC, title={An international case-control study of glutathione transferase and functionally related polymorphisms and risk of primary adult brain tumors.}, author={Judith Schwartzbaum and Anders Ahlbom and Stefan L{\"o}nn and Margareta Warholm and Agneta Rannug and Anssi Auvinen and Helle Collatz Christensen and Roger Henriksson and Christoffer Johansen and Carita Lindholm and Beatrice Susanne Malmer and Tiina Salminen and Minouk J. Schoemaker and Anthony Swerdlow and Maria Feychting}, journal={Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology}, year={2007}, volume={16 3}, pages={559-65} }