An international, multicenter, placebo-controlled trial of paroxetine in adolescents with major depressive disorder.

@article{Berard2006AnIM,
  title={An international, multicenter, placebo-controlled trial of paroxetine in adolescents with major depressive disorder.},
  author={Ray Berard and R. Simon Fong and David J. Carpenter and Christine K Thomason and Christel Wilkinson},
  journal={Journal of child and adolescent psychopharmacology},
  year={2006},
  volume={16 1-2},
  pages={59-75}
}
OBJECTIVE The aim of this study was to examine the efficacy, safety, and tolerability of paroxetine in adolescents with unipolar major depression. METHOD Two hundred eighty-six (286) adolescents with unipolar major depression were randomly assigned to receive either paroxetine or placebo for 12 weeks. RESULTS The proportion of Montgomery-Asberg Depression Rating Scale (MADRS) responders (at least 50% reduction from baseline) for paroxetine and placebo were similar and not statistically… CONTINUE READING
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