An interaction of oxytocin receptors with metabotropic glutamate receptors in hypothalamic astrocytes.

@article{Kuo2009AnIO,
  title={An interaction of oxytocin receptors with metabotropic glutamate receptors in hypothalamic astrocytes.},
  author={John E Kuo and Omid R Hariri and Paul S. Micevych},
  journal={Journal of neuroendocrinology},
  year={2009},
  volume={21 12},
  pages={1001-6}
}
Hypothalamic astrocytes play a critical role in the regulation and support of many different neuroendocrine events, and are affected by oestradiol. Both nuclear and membrane oestrogen receptors (ERs) are expressed in astrocytes. Upon oestradiol activation, membrane-associated ER signals through the type 1a metabotropic glutamate receptor (mGluR1a) to induce an increase of free cytoplasmic calcium concentration ([Ca(2+)](i)). Because the expression of oxytocin receptors (OTRs) is modulated by… CONTINUE READING