An integrative genomics strategy for systematic characterization of genetic loci modulating phenotypes.

@article{Bao2007AnIG,
  title={An integrative genomics strategy for systematic characterization of genetic loci modulating phenotypes.},
  author={Lei Bao and Jeremy Peirce and Mi Zhou and Hongqiang Li and Dan Goldowitz and Robert W. Williams and Lu Lu and Yan Cui},
  journal={Human molecular genetics},
  year={2007},
  volume={16 11},
  pages={
          1381-90
        }
}
Naturally occurring genetic variations may affect certain phenotypes through influencing transcript levels of the genes that are causally related to those phenotypes. Genomic regions harboring common sequence variants that modulate gene expression can be mapped as quantitative trait loci (QTLs) using a newly developed genetical genomics approach. This enables a new strategy for systematically mapping novel genetic loci underlying various phenotypes. In this work, we started from a seed set of… 

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