An integrative characterization of recurrent molecular aberrations in glioblastoma genomes

@inproceedings{Sintupisut2013AnIC,
  title={An integrative characterization of recurrent molecular aberrations in glioblastoma genomes},
  author={Nardnisa Sintupisut and Pei-Ling Liu and Chen-Hsiang Yeang},
  booktitle={Nucleic acids research},
  year={2013}
}
Glioblastoma multiforme (GBM) is the most common and malignant primary brain tumor in adults. Decades of investigations and the recent effort of the Cancer Genome Atlas (TCGA) project have mapped many molecular alterations in GBM cells. Alterations on DNAs may dysregulate gene expressions and drive malignancy of tumors. It is thus important to uncover causal and statistical dependency between 'effector' molecular aberrations and 'target' gene expressions in GBMs. A rich collection of prior… CONTINUE READING

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