An integrated view of the determinants of maximum oxygen uptake.

  title={An integrated view of the determinants of maximum oxygen uptake.},
  author={Peter D. Wagner},
  journal={Advances in experimental medicine and biology},
  • Peter D. Wagner
  • Published 1988 in Advances in experimental medicine and biology
This paper develops an analysis of the interaction between circulatory convective and tissue diffusive O2 transport that explains how VO2 max is set by the integrated response to each and every step in the O2 transport chain from atmosphere to mitochondria. We suggest that it is not useful to search for "the" rate limiting step determining VO2max; rather, all steps contribute. Beyond these basic concepts, the theory accounts for observations of VO2max at altitude, permits experimentally… CONTINUE READING

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