An integrated open framework for thermodynamics of reactions that combines accuracy and coverage

Abstract

MOTIVATION The laws of thermodynamics describe a direct, quantitative relationship between metabolite concentrations and reaction directionality. Despite great efforts, thermodynamic data suffer from limited coverage, scattered accessibility and non-standard annotations. We present a framework for unifying thermodynamic data from multiple sources and… (More)
DOI: 10.1093/bioinformatics/bts317

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