An integrated method to determine meaningful changes in health-related quality of life.

@article{Crosby2004AnIM,
  title={An integrated method to determine meaningful changes in health-related quality of life.},
  author={Ross D. Crosby and Ronette L Kolotkin and Grant R. Williams},
  journal={Journal of clinical epidemiology},
  year={2004},
  volume={57 11},
  pages={
          1153-60
        }
}
OBJECTIVE We describe an integrated method for determining meaningful change in health-related quality of life (HRQOL) that combines information from anchor-based and distribution-based methods and illustrate this method using data aggregated from weight loss studies. STUDY DESIGN AND SETTING A total of 1476 participants in weight loss studies were evaluated at baseline and at 6 months using the Impact of Weight on Quality of Life-Lite (IWQOL-Lite). Severity of baseline impairment was… CONTINUE READING
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